Hotel History
The DeSoto House Hotel is the oldest operating hotel in Illinois, first opening its doors in 1855. Find out more about the DeSoto House History.
The DeSoto Dispatch
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Plan Your Visit
Best place to stay in Galena! In our opinion there isn't a better or more convenient place to stay in historic Galena. On Main Street in the heart of the tourist-happy shopping district. Food always excellent and plentiful in any of the three restaurants. Very comforatable rooms and an excellent staff. Yes they do it right at the DeSoto House.Taylor B. - Chiciago, IL